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Google unveiled AlphaGenome, an AI tool aimed at unravelling the human genome and potentially guiding future disease treatments.
Developed by DeepMind, the model analyses long DNA sequences—up to a million letters—to predict how each nucleotide pair influences cellular processes, including gene start/stop sites and RNA production.
It focuses on non-coding DNA, once deemed “junk,” now seen as a regulator of gene expression. Trained on public data across hundreds of cell and tissue types in humans and mice, AlphaGenome can compare mutated vs. non-mutated sequences at high resolution to map functional elements and their molecular roles.
Open to non-commercial use by about 3,000 scientists in 160 countries, the tool aims to accelerate understanding of the genome and therapeutic development, though experts caution that data quality and environmental factors limit its reach.
